发明名称 |
THERAPEUTIC VACCINES FOR TREATING HERPES SIMPLEX VIRUS TYPE 2 INFECTIONS |
摘要 |
The invention provides methods and kits for inducing a therapeutic immunity in animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. In particular, the invention provides a method of treating animals with an established HSV-2 infection by administering a therapeutic vaccine comprising a priming dose of a nucleic acid encoding an HSV-2 antigen, an initial or first boosting dose comprising the protein form of the antigen encapsulated in liposomes, and one or more subsequent boosting doses comprising both the nucleic acid encoding the HSV-2 antigen and the liposomal-encapsulated protein antigen. |
申请公布号 |
EP2941269(A1) |
申请公布日期 |
2015.11.11 |
申请号 |
EP20140735408 |
申请日期 |
2014.01.07 |
申请人 |
BIOMEDICAL RESEARCH MODELS, INC. |
发明人 |
YANG, KEJIAN;GUBERSKI, DENNIS L. |
分类号 |
A61K39/245;A61K9/127 |
主分类号 |
A61K39/245 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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