Compositions and methods of the present invention relating to B. burgdorferi HtrA sensu lato (BbHtrA) protease activity, its substrates, cleavage products, biological effects and use in detection, diagnosis and/or treatment of Lyme disease are provided.
申请公布号
EP2805168(A4)
申请公布日期
2015.11.11
申请号
EP20130738230
申请日期
2013.01.21
申请人
THE GOVERNMENT OF THE U.S.A AS REPRESENTED BY THESECRETARY OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION;RUSSELL, THERESA, M.;JOHNSON, BARBARA, J.B.