| 发明名称 | Tricyclic fused thiophene derivatives as JAK inhibitors | ||
| 摘要 | The present invention provides tricyclic fused thiophene derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase (JAK) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases. | ||
| 申请公布号 | US9181271(B2) | 申请公布日期 | 2015.11.10 |
| 申请号 | US201314068796 | 申请日期 | 2013.10.31 |
| 申请人 | Incyte Holdings Corporation;Incyte Corporation | 发明人 | Li Yun-Long;Zhu Wenyu;Mei Song |
| 分类号 | C07D495/12;C07D495/14 | 主分类号 | C07D495/12 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A compound, which is ((2R,5S)-5-{2-[(1R)-1-hydroxyethyl]-1H-imidazo[4,5-d]thieno[3,2-b]pyridin-1-yl}tetrahydro-2H-pyran-2-yl)acetonitrile, or a pharmaceutically acceptable salt thereof. | ||
| 地址 | Wilmington DE US | ||