发明名称 |
8-AZABICYCLO[3.2.1]OCTANE COMPOUNDS AS MU OPIOID RECEPTOR ANTAGONISTS |
摘要 |
<p>The invention provides 8-azabicyclo[3.2.1]octane compounds of formula (I), or a pharmaceutically-acceptable salt or solvate thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds. (see formula I)</p> |
申请公布号 |
CA2646409(C) |
申请公布日期 |
2015.11.10 |
申请号 |
CA20072646409 |
申请日期 |
2007.02.28 |
申请人 |
THERAVANCE, INC. |
发明人 |
LONG, DANIEL;CHURCH, TIMOTHY J.;JACOBSEN, JOHN R.;JIANG, LAN;SAITO, DAISUKE ROLAND;STERGIADES, IOANNA;VAN DYKE, PRISCILLA;DALZIEL, SEAN;PREZA, LETICIA |
分类号 |
C07D451/02;A61K31/46;A61P1/10 |
主分类号 |
C07D451/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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