Composition and methods for enhancing surface reflectance

摘要

Microspheres, typically sterile, inert, silica glass microspheres, are dispersed in a carrier suitable for use relative to the object to be imaged and analyzed. In the case of ophthalmic imaging, an ophthalmically-acceptable gel is used and the resulting composition is dispensed into a mammalian eye. The gel and microspheres dispersed therein coat and conform to the surface of the eye. The microspheres enhance reflectance from the eye which improves signal-to-noise ratio and improves imaging quality.

主权项

1. An ophthalmic composition comprising microspheres of sterile, silica glass that enhance reflectance of light from a corneal surface of an eye, dispersed in an inert, ophthalmically-acceptable gel having a viscosity suitable for conforming to at least the corneal surface of the eye and dispersing the microspheres thereover, wherein the composition comprises about 10% w/v or greater of the silica glass microspheres.