发明名称 Inhibition of angiogenesis
摘要 The present invention relates to the microRNA miR-126 and to inhibitors of miR-126 that regulate angiogenesis. The present invention provides compositions and methods for the inhibition of miR-126 and for the inhibition of angiogenesis in vivo.
申请公布号 US9179654(B2) 申请公布日期 2015.11.10
申请号 US200912936732 申请日期 2009.04.07
申请人 CORNELL RESEARCH FOUNDATION, INC. 发明人 Lagos-Quintana Mariana;Rafii Shahin;Chavala Sai H.
分类号 A61K48/00;C07H21/02;C07H21/04;A01K67/027;C12N15/113 主分类号 A61K48/00
代理机构 Scully, Scott, Murphy & Presser, P.C. 代理人 Scully, Scott, Murphy & Presser, P.C.
主权项 1. A method of inhibiting angiogenesis in a subject in need thereof, the method comprising administering to the subject an effective amount of an inhibitor of miR-126, wherein miR-126 is set forth in SEQ ID. NO: 1 or SEQ ID. NO: 2.
地址 Ithaca NY US