发明名称 |
Inhibition of angiogenesis |
摘要 |
The present invention relates to the microRNA miR-126 and to inhibitors of miR-126 that regulate angiogenesis. The present invention provides compositions and methods for the inhibition of miR-126 and for the inhibition of angiogenesis in vivo. |
申请公布号 |
US9179654(B2) |
申请公布日期 |
2015.11.10 |
申请号 |
US200912936732 |
申请日期 |
2009.04.07 |
申请人 |
CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
Lagos-Quintana Mariana;Rafii Shahin;Chavala Sai H. |
分类号 |
A61K48/00;C07H21/02;C07H21/04;A01K67/027;C12N15/113 |
主分类号 |
A61K48/00 |
代理机构 |
Scully, Scott, Murphy & Presser, P.C. |
代理人 |
Scully, Scott, Murphy & Presser, P.C. |
主权项 |
1. A method of inhibiting angiogenesis in a subject in need thereof, the method comprising administering to the subject an effective amount of an inhibitor of miR-126, wherein miR-126 is set forth in SEQ ID. NO: 1 or SEQ ID. NO: 2. |
地址 |
Ithaca NY US |