发明名称 |
METODO PARA PREDECIR LA RESPUESTA AL TRATAMIENTO CON RADIOTERAPIA COMBINADA CON QUIMIOTERAPIA BASADA EN CISPLATINO |
摘要 |
The invention relates to a method for predicting the response to treatment with radiotherapy combined with chemotherapy based on cisplatin in patients suffering from cancer, preferably non-small cell lung cancer, where said method is based on the detection of the presence of methylation of the gene IGFBP-3. The invention also relates to an in vitro method for designing a personalised treatment for an individual suffering from said disease. The method of the invention can be quantitative or semi-quantitative. The invention also relates to a probe for the quantitative detection of the methylation of the gene IGFBP-3, to a kit comprising same, and to the use of said kit for predicting the response of an individual receiving the described treatment.. |
申请公布号 |
ES2527724(B1) |
申请公布日期 |
2015.11.10 |
申请号 |
ES20130030783 |
申请日期 |
2013.05.29 |
申请人 |
FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO LA PAZ;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC);UNIVERSIDAD AUTONOMA DE MADRID;FUNDACION HOSPITAL DE MADRID |
发明人 |
IBANEZ DE CACERES, INMACULADA;BELDA INIESTA, CRISTOBAL;PERNIA ARIAS, OLGA;PERONA ABELLON, ROSARIO;CORTES SEMPERE, MARIA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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