Shape-set textile structure based mechanical thrombectomy systems

摘要

A biomedical shape-set textile structure based mechanical thrombectomy systems and methods are described. In one of the embodiments, the mechanical thrombectomy device can be customized to the length of the clot in each patient. In one of the embodiments, the mechanical thrombectomy device because of the textile structure has a very low overall profile or thickness that is less than 0.0125 inches (0.317 mm) and therefore can be deployed within microcatheters with inner lumen diameter as small as 0.014 inches (0.355 mm).

主权项

1. A thrombectomy device comprising:
an elongate support structure comprising a plurality of shape-memory and radiopaque wires woven to form a textile fabric having a collapsed state and an expanded state, the elongate support structure comprising:
a plurality of self-expanding generally spherical bulbs in the expanded state comprising:
a first bulb;a second bulb distal to the first bulb, the first bulb and the second bulb having a first diameter;a third bulb distal to the second bulb;a fourth bulb distal to the third bulb, the third bulb and the fourth bulb having a second diameter smaller than the first diameter;a fifth bulb distal to the fourth bulb;a sixth bulb distal to the fifth bulb;a seventh bulb distal to the sixth bulb, the fifth bulb, the sixth bulb, and the seventh bulb having a third diameter smaller than the second diameter;an eighth bulb distal to the seventh bulb;a ninth bulb distal to the eighth bulb; anda tenth bulb distal to the ninth bulb, the eighth bulb, the ninth bulb, and the tenth bulb having a fourth diameter smaller than the third diameter,necks longitudinally between and radially inward of the self-expanding bulbs, anda distal neck distal to and radially inward of a distal-most bulb of the self-expanding bulbs, the distal neck comprising a coated distal end; a delivery system comprising a hypotube comprising two longitudinally interspersed and circumferentially staggered cut patterns, the cut patterns each comprising a plurality of rows each comprising two longitudinally-spaced kerfs angled with respect to a longitudinal axis of the hypotube and comprising rounded edges, wherein a longitudinally-spacing of the kerfs varies along the hypotube; and a bonding zone where the delivery system is coupled to the elongate support structure, the bonding zone comprising a radiopaque marker band.