Porous bidirectional bellowed tracheal reconstruction device

摘要

Implantable splinting devices for supporting a passageway defect in a patient that is formed from one or more support structures including a polymer or a polymer and acellularized tissue matrix that define a structural component that substantially conforms to a defective passageway of the patient. The structural component also has a plurality of pores. The implantable splinting device is capable of being placed around a trachea, a bronchi, an esophagus and a blood vessel of a patient. The implantable splinting device may also be configured for placement between the trachea, and the esophagus of a patient.

主权项

1. An implantable splinting device for supporting a defect in a passageway of a human or other animal subject comprising:
one or more bellow support structures together defining a structural component that substantially conforms to at least a portion of the passageway and a plurality of apertures defined in at least a portion of the one or more bellow support structures, wherein the one or more bellow support structures comprise a biocompatible polymeric material, so that the structural component is capable of restricting displacement to less than 10% under a direct compression load of about 50 Newtons (N), while permitting outward radial displacement of at least 100% of an initial diameter of the structural component under non-stress conditions under a radial pressure of about 50 Newtons (N).