发明名称 Aromatic ring compound
摘要 Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I):; wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity, and is useful as an agent for the prophylaxis or treatment of diabetes and the like.
申请公布号 US9181186(B2) 申请公布日期 2015.11.10
申请号 US201314377951 申请日期 2013.02.12
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 Miwatashi Seiji;Suzuki Hideo;Okawa Tomohiro;Miyamoto Yasufumi;Yamasaki Takeshi;Hitomi Yuko;Hirata Yasuhiro
分类号 C07D213/64;C07D405/14;C07D401/12;C07D239/34;C07D213/30;C07D213/68;C07D213/69;C07D213/55;C07D403/12 主分类号 C07D213/64
代理机构 Wenderoth, Lind & Ponack, L.L.P. 代理人 Wenderoth, Lind & Ponack, L.L.P.
主权项 1. A compound represented by the formula (I): wherein ring A is an optionally further substituted 6-membered aromatic ring; ring B is an optionally further substituted 6-membered aromatic heterocycle; ring C is an optionally further substituted 6-membered aromatic ring; Y is —NR4A—, —CR4BR4C— or —O—; R1 is a substituent; R2 and R3 are each independently a hydrogen atom or a substituent; and R4A, R4B and R4C are each independently a hydrogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted C2-6 alkenyl group, an optionally substituted C2-6 alkynyl group, or an optionally substituted C3-7 cycloalkyl group, or a salt thereof.
地址 Osaka JP