发明名称 |
Aromatic ring compound |
摘要 |
Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I):;
wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity, and is useful as an agent for the prophylaxis or treatment of diabetes and the like. |
申请公布号 |
US9181186(B2) |
申请公布日期 |
2015.11.10 |
申请号 |
US201314377951 |
申请日期 |
2013.02.12 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
Miwatashi Seiji;Suzuki Hideo;Okawa Tomohiro;Miyamoto Yasufumi;Yamasaki Takeshi;Hitomi Yuko;Hirata Yasuhiro |
分类号 |
C07D213/64;C07D405/14;C07D401/12;C07D239/34;C07D213/30;C07D213/68;C07D213/69;C07D213/55;C07D403/12 |
主分类号 |
C07D213/64 |
代理机构 |
Wenderoth, Lind & Ponack, L.L.P. |
代理人 |
Wenderoth, Lind & Ponack, L.L.P. |
主权项 |
1. A compound represented by the formula (I): wherein ring A is an optionally further substituted 6-membered aromatic ring; ring B is an optionally further substituted 6-membered aromatic heterocycle; ring C is an optionally further substituted 6-membered aromatic ring; Y is —NR4A—, —CR4BR4C— or —O—; R1 is a substituent; R2 and R3 are each independently a hydrogen atom or a substituent; and R4A, R4B and R4C are each independently a hydrogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted C2-6 alkenyl group, an optionally substituted C2-6 alkynyl group, or an optionally substituted C3-7 cycloalkyl group, or a salt thereof. |
地址 |
Osaka JP |