Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer-amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-&bgr; plaque deposits characteristic of Alzheimer's Disease.
申请公布号
HK1203827(A1)
申请公布日期
2015.11.06
申请号
HK20150104390
申请日期
2015.05.08
申请人
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;ALZECA BIOSCIENCES LLC;BOARD OF REGENTS OF THE UNIVERSITY OF HOUSTON SYST
发明人
ANNAPRAGADA, ANANTH A;ERIKSEN, JASON, L. J L;TANIFUM, ERIC, A. E A;DASGUPTA, INDRANI I;COOK, STEPHEN, C. S C
