发明名称 |
ANTI -TRANSGLUTAMINASE 2 ANTIBODIES - 2 |
摘要 |
<p>The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer.</p> |
申请公布号 |
HK1203974(A1) |
申请公布日期 |
2015.11.06 |
申请号 |
HK20150104401 |
申请日期 |
2015.05.11 |
申请人 |
MEDICAL RESEARCH COUNCIL TECHNOLOGY |
发明人 |
JOHNSON, TIM;WATSON, PHIL;MATTHEWS, DAVID;BROWN, ALEX |
分类号 |
C07K |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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