The present invention relates to the 1H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta (GSK-3&bgr;) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.
申请公布号
HK1203930(A1)
申请公布日期
2015.11.06
申请号
HK20150104324
申请日期
2015.05.06
申请人
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.
发明人
ALISI, Maria Alessandra;CAZZOLLA, Nicola;DRAGONE, Patrizia;FURLOTTI, Guido;MAUGERI, Caterina;OMBRATO, Rosella;MANCINI, Francesca