发明名称 METHODS FOR TREATING HEADACHE
摘要 A headache can be treated more effectively by co-administration of a botulinum toxin and a triptan drug to a patient and/or the effectiveness of a triptan medication can be increased. The botulinum toxin can be botulinum toxin type A and the botulinum toxin can be administered to or to the vicinity of where a patient experiences or is predisposed to experience pain or a headache.
申请公布号 US2015313974(A1) 申请公布日期 2015.11.05
申请号 US201514797552 申请日期 2015.07.13
申请人 Allergan, Inc. 发明人 Turkel Catherine C.;Brin Mtichell F.
分类号 A61K38/48;A61K9/00 主分类号 A61K38/48
代理机构 代理人
主权项 1. A method for reducing the occurrence of or alleviating a headache in a patient with tension-type headaches, the method comprising local administration by injection of a composition comprising a botulinum toxin type A, wherein the number of injection sites is 23 to 58, the number of muscle areas injected is 6 to 7 and the botulinum toxin type A dose is 105 to 260 units, and wherein at least the frontal/glabellar, occipitalis, temporalis, semispinalis, splenius capitis or trapezius muscles are injected.
地址 Irvine CA US