| 摘要 |
A library of macrocyclic compounds of the formula (I);where part (A) is a;;bivalent radical, a —(CH2)y— bivalent radical or a covalent bond;
where part (B) is a;;bivalent radical, a —(CH2)z— bivalent radical, or a covalent bond;
where part (C) is a;;bivalent radical, a —(CH2)t— bivalent radical, or a covalent bond; and
where part (T) is a —Y-L-Z— radical wherein Y is CH2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed. |
