发明名称 CRYSTALLINE ANTIFUNGAL COMPOUNDS
摘要 PROBLEM TO BE SOLVED: To provide novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms.SOLUTION: The present invention provides the specific crystalline forms I, II, III, IV, V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.
申请公布号 JP2015193642(A) 申请公布日期 2015.11.05
申请号 JP20150137404 申请日期 2015.07.09
申请人 STIEFEL LABORATORIES INC;PALAU PHARMA SA 发明人 PAREDES ANTONIO CANOVAS;JAVIER BARTROLI ORPI;ELIES MOLINS GRAU;ANNA ROIG SERRA;KEVIN MAYER;KEITH LORIMER
分类号 C07D403/06;A61K31/506;A61P31/04;A61P31/10;A61P33/02 主分类号 C07D403/06
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