发明名称 |
FARNESOID X RECEPTOR ANTAGONISTS |
摘要 |
Provided herein are Famesoid X receptor (FXR) antagonists having the structure of formula (I), and pharmaceutical compositions comprising the compound of formula (I) and a pharmaceutically acceptable excipient. Also provided are methods of antagonizing FXR and methods of treating metabolic disease in a subject in need thereof, comprising administering an effective amount of the FXR antagonist of formula (I) to a subject. |
申请公布号 |
WO2015116856(A3) |
申请公布日期 |
2015.11.05 |
申请号 |
WO2015US13596 |
申请日期 |
2015.01.29 |
申请人 |
CITY OF HOPE;FOREMAN, BARRY |
发明人 |
FOREMAN, BARRY;YU, DONNA |
分类号 |
A61K31/4155;A61K31/18;C07D231/02 |
主分类号 |
A61K31/4155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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