| 发明名称 |
COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CANCER |
| 摘要 |
Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases. |
| 申请公布号 |
US2015313898(A1) |
申请公布日期 |
2015.11.05 |
| 申请号 |
US201514729642 |
申请日期 |
2015.06.03 |
| 申请人 |
University of Maryland, Baltimore |
发明人 |
Tomkinson Alan E.;Chen Helen Xi;Dziegielewska Barbara;Mackerell Alexander D.;Zhong Shijun;Wilson Gerald M. |
| 分类号 |
A61K31/505;G06F19/16;A61K31/165;G06F19/00;A61K31/255;A61N5/10;G01N21/64;C40B30/02;A61K31/166 |
主分类号 |
A61K31/505 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
Baltimore MD US |
