| 发明名称 |
TOPICAL FORMULATIONS FOR THE PREVENTION AND TREATMENT OF ALOPECIA AND INHIBITION OF HAIR GROWTH |
| 摘要 |
The present invention discloses formulations for the treatment and prevention of alopecia; the formulations comprise angiotensin-(1-7) and/or their analogues, encapsulated in ultradeformable vesicles prepared from specific combinations of phospholipids and surfactants, which confer efficacy to topical application in the control of hair growth, which indicates their great potential for the prevention and treatment of alopecia. The invention also describes formulations containing A779 Mas receptor antagonist of angiotensin-(1-7) and/or their analogues and their use in inhibiting hair growth. |
| 申请公布号 |
US2015313829(A1) |
申请公布日期 |
2015.11.05 |
| 申请号 |
US201314647348 |
申请日期 |
2013.11.26 |
| 申请人 |
QUEIROGA LAUTNER Roberto;CAMPOS VILLELA Daniel;ARAUJO FRAGA DA SILVA Rodrigo;FERREIRA Anderson José;DA SILVA Elisangela Fátima;UNIVERSIDADE FEDERAL DE MINAS GERAIS -UFMG |
发明人 |
Frezard Frederic Jean Georges;Dos Santos Robson Augusto Souza;Correa De Oliveira Bahia Ana Paula;Silva Neiva Caldeira;Lautner Roberto Queiroga;Villela Daniel Campos;Araujo Fraga Da Silva Rodrigo;Ferreira Anderson Jose;Da Silva Elisangela Fatima |
| 分类号 |
A61K8/64;A61K8/55;A61Q7/02;A61Q7/00 |
主分类号 |
A61K8/64 |
| 代理机构 |
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代理人 |
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| 主权项 |
1. A topical composition comprising 0.1 to 100 μg/ml of one or more angiotensin compounds of SEQ ID NO: 2 wherein X and Y can be any amino acid, and further comprising 0.1 to 3% (w/v) surfactant, 1 to 20% (w/v) phospholipid and 0 to 30% (v/v) ethanol. |
| 地址 |
US |
