发明名称 TREATMENT OF CROHN'S DISEASE WITH DELAYED-RELEASE 6-MERCAPTOPURINE
摘要 Methods of treating patients suffering from Crohn's disease or ulcerative colitis who did not experience a clinical response to previous thiopurine administration, or suffered side effects from previous thiopurine administration, by administering a delayed release pharmaceutical composition comprising 6-mercaptopurine are disclosed. Methods of treating patients suffering from Crohn's disease or ulcerative colitis who are also being administered a steroid, 5-aminosalicylic acid, or an antibiotic by adjunctively administering a delayed release pharmaceutical composition comprising 6-mercaptopurine are also disclosed.
申请公布号 US2015313904(A1) 申请公布日期 2015.11.05
申请号 US201514701201 申请日期 2015.04.30
申请人 KOLATCH Brenda;HOTOVELY-SALOMON Anna 发明人 KOLATCH Brenda;HOTOVELY-SALOMON Anna
分类号 A61K31/52;A61K9/00 主分类号 A61K31/52
代理机构 代理人
主权项 1. A method of treating a human patient suffering from Crohn's disease (CD) or ulcerative colitis (UC) who did not experience a clinical response to previous thiopurine administration, comprising periodically administering to the human patient a delayed release pharmaceutical composition comprising a pharmaceutically acceptable carrier and an amount of 6-mercaptopurine (6-MP) effective to treat the human patient.
地址 Jerusalem IL