摘要 |
Provided herein are methods of treating a cardiomyopathy in a subject by administering directly to, or expressing locally in, a weakened, ischemic, and/or peri-infarct region of myocardial tissue of the subject an amount of SDF-1 effective to cause functional improvement in at least one of the following parameters: left ventricular volume, left ventricular area, left ventricular dimension, cardiac function, 6-minute walk test, or New York Heart Association (NYHA) functional classification. Methods of treating subjects with advanced ischemic cardiomyopathy are further disclosed herein. |
申请人 |
PENN, MARC, S.;ARAS, RAHUL;PASTORE, JOSEPH;MILLER, TIMOTHY, J. |
发明人 |
PENN, MARC, S.;ARAS, RAHUL;PASTORE, JOSEPH;MILLER, TIMOTHY, J. |