发明名称 METHOD FOR ACTIVATION OF STEM CELL PROLIFERATION AND INCREASE OF STEM CELLS RESISTENCE TO NEGATIVE IMPACTS
摘要 Method for activation of stem cells' proliferation and increase in the resistance of the stem cells to negative impacts, without use of high-frequency electro-magnetic field, is provided. The technical result is achieved due to the treating of the cells culture with a weak low-frequency magnetic field. The proposed method includes: 1) Increase in number of the human stem cells in the culture after their exposure to a weak magnetic field over a representative for the given cell culture doubling half-period (for 24 hours, number of cells increases 2.5 times-at full doubling period of the intact cells equals to 48 hours); 2) Increase of amplitude of self-magnetic irradiation of the initial culture of the stem cells, which indicates increased activity. 3) Double increase in stability of the human stem cells with respect to the development of apoptosis and synchronization of the cells predominantly in G1 phase.
申请公布号 US2015315563(A1) 申请公布日期 2015.11.05
申请号 US201214432384 申请日期 2012.10.02
申请人 ORLOVA Elena Vladimirovna;MAEVSKY Evgeny Ilich;KLUBKOV Vladimir Konstantinovich 发明人 ORLOVA Elena Vladimirovna;MAEVSKY Evgeny Ilich;KLUBKOV Vladimir Konstantinovich
分类号 C12N13/00 主分类号 C12N13/00
代理机构 代理人
主权项 1. A method for treating stem cells by a magnetic field, the method comprising: exposing the stem cells to an alternating magnetic field, wherein: the magnetic field is applied collinearly to Earth magnetic field; andthe magnetic field activates proliferation and increases resistance of the stem cells to negative impacts that decrease normal metabolism, homeostasis, proliferation, differentiation and growth of stem cells.
地址 US