发明名称 MULTISPECIFIC ANTIBODIES
摘要 The invention provides multispecific antibodies and methods of making and using such antibodies.
申请公布号 US2015315290(A1) 申请公布日期 2015.11.05
申请号 US201514665697 申请日期 2015.03.23
申请人 Genentech, Inc. 发明人 BOSTROM Jenny M.;FUH Germaine
分类号 C07K16/32;A61K45/06;A61K39/395;C07K16/22 主分类号 C07K16/32
代理机构 代理人
主权项 1. A method of treating a tumor in a subject, said method comprising administering to said subject an antibody comprising an HVR-L1, HVR-L2, HVR-L3, HVR-H1, HVR-H2, and HVR-H3, wherein each, in order, comprises the sequence of SEQ ID NO: 1, 2, 3, 4, 5, and 6, wherein said antibody specifically binds HER2 and VEGF, and wherein said administering is for a time and in an amount sufficient to treat or prevent said tumor in said subject.
地址 South San Francisco CA US
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