| 发明名称 |
SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF |
| 摘要 |
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a [(1-Piperazinyl)-4-pyridinylmethyl]-Naphtho[1,2-b]furan structure which function as inhibitors of Mcl-1 protein, and their use as therapeutics for the treatment of cancer and other diseases. |
| 申请公布号 |
EP2831067(A4) |
申请公布日期 |
2015.11.04 |
| 申请号 |
EP20130767518 |
申请日期 |
2013.03.29 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
NIKOLOVSKA-COLESKA, ZANETA;BAJWA, NAVAL;LIAO, CHENZHONG;MIAO, LEI |
| 分类号 |
C07D407/14;A61K31/496;A61K31/5377;A61P35/00;C07D413/14 |
主分类号 |
C07D407/14 |
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