发明名称 生物製剤の製造および精製を改善するための薬理学的シャペロンの利用
摘要 The present invention provides methods for improving the production of recombinant proteins through the use of pharmacological chaperones for the recombinant proteins. As exemplified by the present invention, the binding of a pharmacological chaperone to a recombinant protein expressed by a cell can stabilize the protein and increase export of the protein out of the cell's endoplasmic reticulum, and increase secretion of the protein by the cell.
申请公布号 JP5805630(B2) 申请公布日期 2015.11.04
申请号 JP20120513221 申请日期 2010.05.26
申请人 アミカス セラピューティックス インコーポレイテッド 发明人 フン・ブイ・ド
分类号 C12P21/02;C12N9/24;C12N9/38 主分类号 C12P21/02
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