| 发明名称 |
DRY GRANULATION PROCESS FOR PRODUCING TABLET COMPOSITIONS OF METFORMIN AND COMPOSITIONS THEREOF |
| 摘要 |
The present invention pertains to a novel dry granulation method for producing tablet compositions of Metformin as well as a combination thereof with DPP-4 inhibitors. The method involves use of a mixture of MCC&DCPA in specific amounts to bring solution to the problems of conventional processes such as poor compaction, friability and stability. |
| 申请公布号 |
EP2938362(A1) |
申请公布日期 |
2015.11.04 |
| 申请号 |
EP20130834323 |
申请日期 |
2013.12.17 |
| 申请人 |
ZENTIVA SAGLIK ÜRÜNLERI SAN. VE TIC. A.S. |
发明人 |
ASKAR, GÖZDE;ORAN, UMUT;BITIK, NACI;ADIYAMAN, MUSTAFA |
| 分类号 |
A61K45/06;A61K9/20;A61K31/155;A61K31/40 |
主分类号 |
A61K45/06 |
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