发明名称 |
MONOCLONAL ANTIBODY AGAINST NECROSIS MARKER PRDX4 AND USE THEREOF |
摘要 |
[PROBLEM] To provide a monoclonal antibody against a biomarker which shows high specificity and can be effectively used in detection and diagnosis of various lesions relevant to various kinds of carcinomas and foci of necrosis, and so forth. [MEANS] A monoclonal antibody against a necrosis marker consisting the following amino acid sequence: (1) the amino acid sequence of SEQ ID NO: 1, or (2) an amino acid sequence having substitution, deletion and/or insertion of one or several amino acid residues in the amino acid sequence of (1) or sharing a homology of 90% or more with the amino acid sequence of (1), and showing the same function, activity or property as that of the amino acid sequence of (1) as a protein. |
申请公布号 |
EP2546269(B8) |
申请公布日期 |
2015.11.04 |
申请号 |
EP20110753352 |
申请日期 |
2011.03.08 |
申请人 |
FUJIFILM CORPORATION |
发明人 |
SUGANO, SUMIO;KANZAKI, YUKARI;SAGA, TSUNEO;TSUJI, ATSUSHI |
分类号 |
C07K16/40;A61K39/395;A61K45/00;A61K49/00;A61P1/16;A61P1/18;A61P9/00;A61P9/10;A61P21/00;A61P35/00;C12N15/09;C12Q1/02;C12Q1/68;G01N33/53 |
主分类号 |
C07K16/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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