| 发明名称 |
PRODUCTION OF RECOMBINANT PROTEINS WITH SIMPLE GLYCOFORMS |
| 摘要 |
The present invention provides cell lines deficient in mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase I (Mgat1). Also provided are methods for producing the Mga1 deficient cell lines and methods for using the Mgat1 deficient cell lines for the production of recombinant proteins having simple glycoforms. |
| 申请公布号 |
EP2802654(A4) |
申请公布日期 |
2015.11.04 |
| 申请号 |
EP20130735783 |
申请日期 |
2013.01.10 |
| 申请人 |
SIGMA-ALDRICH CO. LLC |
发明人 |
LIN, NAN;SEALOVER, NATALIE;GEORGE, HENRY;KAYSER, KEVIN |
| 分类号 |
C12N15/00;C12N5/02;C12N15/87;C12P21/00 |
主分类号 |
C12N15/00 |
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