| 发明名称 |
METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX |
| 摘要 |
The present invention b directed to CA IX inhibitors that conform to Formula I where the substituents X, A, B, D, E, E′ and G are as defined above. Also described are Pt, 64Cu, 186Re, 188Re and 99mTc metal complexes of Formula I compounds which find use as candidate agents for imaging tumors. |
| 申请公布号 |
EP2800471(A4) |
申请公布日期 |
2015.11.04 |
| 申请号 |
EP20130733617 |
申请日期 |
2013.01.04 |
| 申请人 |
MOLECULAR INSIGHT PHARMACEUTICALS, INC. |
发明人 |
BABIC, JOHN, W;ZIMMERMAN, CRAIG;JOYAL, JOHN;LU, SHAWN;HILLIGER, SHAWN;MARESCA, KEVIN, P;MARQUIS, JOHN |
| 分类号 |
C07D233/64;A61K51/04;C07F13/00 |
主分类号 |
C07D233/64 |
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