| 主权项 |
1. A method of treating a patient comprising:
a. determining a quantified expression level of mir-328, mir-222, mir-197, and mir-21 RNA in a test thyroid tissue sample from the patient to obtain a test dataset of expression levels; b. comparing the test dataset of expression levels of mir-328, mir-222, mir-197, and mir-21 to a malignant thyroid dataset and to a benign thyroid dataset; c. determining whether a test dataset of expression levels is significantly within a malignant thyroid dataset or within a benign thyroid dataset to assess whether the test thyroid tissue sample is benign or malignant; and d. treating the patient for malignant thyroid cancer if the test dataset of expression levels is significantly within a malignant thyroid dataset; wherein the test dataset of expression levels comprises a collection of quantified expression levels of mir-328, mir-222, mir-197, and mir-21 RNA in a test thyroid tissue sample from the patient; wherein the malignant thyroid dataset comprises a collection of quantified expression levels of mir-328, mir-222, mir-197, and mir-21 RNA from malignant thyroid tissue samples; and wherein the benign thyroid dataset comprises a collection of quantified expression levels of mir-328, mir-222, mir-197, and mir-21 RNA from benign, healthy, and/or non-cancerous thyroid tissue samples. |
