System and method for sensing intraocular pressure

摘要

Systems and methods of sensing intraocular pressure are described. An example miniaturized intraocular pressure (IOP) monitoring system is provided using a nanophotonics-based implantable IOP sensor with remote optical readout that can be adapted for both patient and research use. A handheld detector optically excites the pressure-sensitive nanophotonic structure of the IOP-sensing implant placed in the anterior chamber and detects the reflected light, whose optical signature changes as a function of IOP. Optical detection eliminates the need for large, complex LC structures and simplifies sensor design. The use of nanophotonic components improves the sensor's resolution and sensitivity, increases optical readout distance, and reduces its size by a factor of 10-30 over previous implants. Its small size and convenient optical readout allows frequent and accurate self-tracking of IOP by patients in home settings.

主权项

1. A method for sensing pressure, the method comprising:
establishing a gap between first and second membranes at a first pressure, the first and second membranes comprising nanophotonic components; transmitting a first beam of light to the nanophotonic components; measuring a first reflectance of the light off of the nanophotonic components at the first pressure and determining a first resonance by detecting a dip in reflectance; changing the gap between first and second membranes in response to a second pressure; transmitting a second beam of light to the nanophotonic components; measuring a second reflectance of the light off of the nanophotonic components at the second pressure and determining a second resonance by detecting a dip in reflectance; and calculating the second pressure using the difference between the first resonance and second resonance.