发明名称 |
Bioabsorbable polymeric compositions, processing methods, and medical devices therefrom |
摘要 |
Novel bioabsorbable polymeric blends are disclosed. The blends have a first component that is a polylactide polymer or a copolymer of lactide and glycolide and a second component that is poly(p-dioxanone) polymer. The novel polymeric blends provide medical devices having dimensional stability. Also disclosed are novel bioabsorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture. |
申请公布号 |
US9173979(B2) |
申请公布日期 |
2015.11.03 |
申请号 |
US201314084932 |
申请日期 |
2013.11.20 |
申请人 |
Ethicon, Inc. |
发明人 |
Kelly Brian M.;Jamiolkowski Dennis D.;DeFelice Christopher |
分类号 |
A61K47/34;A61F2/00;A61F2/82;A61B17/00;A61B17/04;A61B17/08;A61B17/64;A61B17/84;A61B17/86;C08L67/00;A61L31/04;A61B17/064;C08L67/04;A61L31/14;A61L31/16 |
主分类号 |
A61K47/34 |
代理机构 |
|
代理人 |
Skula E. Richard |
主权项 |
1. A method of manufacturing a bioabsorbable medical device, comprising the steps of:
processing a bioabsorbable polymer blend comprising 78 weight percent to 82 weight percent of a first bioabsorbable polymer and 18 weight percent to 22 weight percent of a second bioabsorbable polymer, the first bioabsorbable polymer comprising a lactide-rich polymer comprising 95 mol percent to 70 mol percent polymerized lactide and 5 mol percent to 30 mol percent polymerized glycolide, and the second bioabsorbable polymer comprising poly(p-dioxanone), wherein the maximum weight percent of poly(p-dioxanone) in the polymer blend is 22 weight percent and the minimum weight percent of poly(p-dioxanone) in the polymer blend depends upon the molar amount of polymerized lactide in the lactide-rich polymer and is calculated by the expression:
Minimum Weight Percent Poly(p-dioxanone)=(215.6212/Mol Percent Polymerized Lactide)27027 and forming a bioabsorbable medical device from the polymer blend, wherein the polymer blend provides dimensional stability to the formed device. |
地址 |
Somerville NJ US |