发明名称 |
<i>Cistus </i>extract containing enriched secondary plant ingredients |
摘要 |
The invention relates to a method for producing an extract containing at least 40% (m/m) of polyphenols from Cistus creticus L., said method comprising the following steps: plant parts are extracted from Cistus creticus L. using an extraction agent selected from the group comprising water, alcohols and mixtures thereof; the extraction residues are removed; the extraction agent is at least partially removed; redissolution is carried out in an aqueous solvent and the undissolved constituents are removed; and selective enriching is carried out by means of either a) a two-phase extraction, and b) a membrane filtration. |
申请公布号 |
US9173912(B2) |
申请公布日期 |
2015.11.03 |
申请号 |
US200912990878 |
申请日期 |
2009.05.06 |
申请人 |
Finzelberg GmbH & Co. KG |
发明人 |
Feistel Bjoern;Walbroel Bernd |
分类号 |
A61K36/752;A61K36/185 |
主分类号 |
A61K36/752 |
代理机构 |
Dardi & Herbert, PLLC |
代理人 |
Dardi & Herbert, PLLC ;Dardi Peter S. |
主权项 |
1. An enriched extract comprising at least 40% (w/w) polyphenols from Cistus creticus L., obtained by a process comprising the steps of:
a. mixing aerial plant parts of Cistus creticus L. with an extractant solvent selected from the group consisting of water, methanol, ethanol, 1-propanol, 2-propanol and mixtures thereof, to produce an extraction mixture; b. removing extraction residues and at least partially removing the extractant solvent from the extraction mixture to produce a crude extract; c. redissolving the crude extract in an aqueous solvent having at least 50% (w/w) water, and removing insoluble components to produce a refined extract; d. enriching the refined extract by at least one of the following steps: 1. solid-phase extraction, wherein the polyphenols bind to the solid phase and are eluted by more lipophilic solvents, 2. liquid-liquid extraction, where in the organic solvent phase is the product phase; 3. membrane filtration, wherein the retentate is the product phase. |
地址 |
Andemach DE |