| 发明名称 | Methods of treating muscular wasting diseases using NF-KB activation inhibitors | ||
| 摘要 | Methods for treating muscular wasting diseases such as Duchenne muscular dystrophy are disclosed. Specifically, the methods include administering to a subject in need of treatment for a muscular wasting disease, an NF-κB activation inhibitor capable of blocking the activation of NF-κB. | ||
| 申请公布号 | US9173920(B2) | 申请公布日期 | 2015.11.03 |
| 申请号 | US201313867795 | 申请日期 | 2013.04.22 |
| 申请人 | TheraLogics, Inc. | 发明人 | Guttridge Denis C.;Baldwin Albert S. |
| 分类号 | A61K38/00;A61K38/08;A61K38/04;A61K38/16;A61K31/00;A61K31/05;A61K31/12;A61K31/335;A61K31/365;A61K31/436;A61K31/454;A61K31/4745;A61K38/17 | 主分类号 | A61K38/00 |
| 代理机构 | Senniger Powers LLP | 代理人 | Senniger Powers LLP |
| 主权项 | 1. A method of treating Duchenne muscular dystrophy in a subject, the method comprising administering to the subject an NF-κB activation inhibitor comprising: a polypeptide having the amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 17. | ||
| 地址 | Chapel Hill NC US | ||