发明名称 Fluid associated with adult stem cells for medical, cosmetic, and veterinary use
摘要 Apparatus and process to create, expand, and localize the population of stem cells in adult tissues by placing a foreign body either in omentum or in the subcutaneous tissue. The apparatus 1) traps the granulation fluid, cells a fluid rich in a myriad of growth factors, 2) mobilizes and concentrates free-floating stem cells in the granulation fluid, and 3) stimulates the growth of a new tissue around the apparatus, which provides another source of stem cells. Stem cells obtained by this process can be used as freshly isolated or after culturing, which can be used for wound healing, treating diseases, and regenerating organs in animals and humans. The granulation fluid could substitute the stem cells in many of their applications and offers the convenience of an injectable medicine for treating animal and human diseases.
申请公布号 US9173903(B2) 申请公布日期 2015.11.03
申请号 US201012855760 申请日期 2010.08.13
申请人 发明人 Singh Ashok K.
分类号 A61P25/00;A61P3/10;A61K9/00;A61P29/00;A61Q19/08;A61M1/00;C12N5/02;A61K9/70;C12N5/07;A61K35/12;A61K38/18;A61K8/02;A61P17/02;A61K39/00;A61P9/00;A61P37/04;A61K35/24 主分类号 A61P25/00
代理机构 Leydig, Voit & Mayer, Ltd. 代理人 Leydig, Voit & Mayer, Ltd.
主权项 1. A method for treating a condition associated with damaged or diseased tissue in a patient, the method comprising administering to the patient a therapeutically effective amount of fluid isolated from a granuloma induced by a foreign body implanted under the skin or in the omentum of a live mammal, wherein the fluid so obtained contains albumin, globulins and at least 2 ng/mL of vascular endothelial growth factor (VEGF), and exceeds FBS in potency for promoting the growth of HK and primary mesangial cells in culture media, and the method results in an improvement in the patient's condition.
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