发明名称 |
Methods of treating autism spectrum disorders and compositions for same |
摘要 |
Disclosed are compositions that inhibit brain blood vessel leakage, compositions for treating autism spectrum disorders, methods of treating autism spectrum disorders, and methods of screening for an autism spectrum disorder. |
申请公布号 |
US9176146(B2) |
申请公布日期 |
2015.11.03 |
申请号 |
US200912534571 |
申请日期 |
2009.08.03 |
申请人 |
Theta Biomedical Consulting & Development Co., Inc. |
发明人 |
Theoharides Theoharis C. |
分类号 |
A61K31/451;A61K31/352;A61K31/4545;A61K31/495;A61K31/519;A61K31/55;A61K36/63;G01N33/68;A61K31/00;A61K45/06 |
主分类号 |
A61K31/451 |
代理机构 |
Wilmer Cutler Pickering Hale and Dorr LLP |
代理人 |
Wilmer Cutler Pickering Hale and Dorr LLP |
主权项 |
1. A method of treating an autism spectrum disorder, comprising administering to a subject in need thereof an effective amount of a composition comprising one or more flavonoids, wherein the one or more flavonoids are present in an amount of 10-3,000 mg per tablet or capsule and the flavonoids comprise luteolin, and optionally, a serotonin blocker, a histamine-1 receptor antagonist, a histamine-3 receptor agonist, an antipsychotic agent, a heavy metal chelator, and olive kernel extract and, wherein the composition inhibits brain blood vessel leakage. |
地址 |
Brookline MA US |