发明名称 Methods of treating autism spectrum disorders and compositions for same
摘要 Disclosed are compositions that inhibit brain blood vessel leakage, compositions for treating autism spectrum disorders, methods of treating autism spectrum disorders, and methods of screening for an autism spectrum disorder.
申请公布号 US9176146(B2) 申请公布日期 2015.11.03
申请号 US200912534571 申请日期 2009.08.03
申请人 Theta Biomedical Consulting & Development Co., Inc. 发明人 Theoharides Theoharis C.
分类号 A61K31/451;A61K31/352;A61K31/4545;A61K31/495;A61K31/519;A61K31/55;A61K36/63;G01N33/68;A61K31/00;A61K45/06 主分类号 A61K31/451
代理机构 Wilmer Cutler Pickering Hale and Dorr LLP 代理人 Wilmer Cutler Pickering Hale and Dorr LLP
主权项 1. A method of treating an autism spectrum disorder, comprising administering to a subject in need thereof an effective amount of a composition comprising one or more flavonoids, wherein the one or more flavonoids are present in an amount of 10-3,000 mg per tablet or capsule and the flavonoids comprise luteolin, and optionally, a serotonin blocker, a histamine-1 receptor antagonist, a histamine-3 receptor agonist, an antipsychotic agent, a heavy metal chelator, and olive kernel extract and, wherein the composition inhibits brain blood vessel leakage.
地址 Brookline MA US