| 发明名称 | Pharmaceutical solid preparation | ||
| 摘要 | An object of the present invention is to provide a gradual disintegration-type, sustained-release pharmaceutical solid preparation whose pharmacologically active substance release behavior is controlled. The solid pharmaceutical preparation of the present invention is a matrix-type preparation containing: (a) a pharmacologically active substance; (b) calcium polycarbophil; and (c) a specific sugar and/or sugar alcohol. | ||
| 申请公布号 | US9173844(B2) | 申请公布日期 | 2015.11.03 |
| 申请号 | US200913062389 | 申请日期 | 2009.08.26 |
| 申请人 | OTSUKA PHARMACEUTICAL CO., LTD. | 发明人 | Suzuki Kai |
| 分类号 | A61K9/14;A61K9/20 | 主分类号 | A61K9/14 |
| 代理机构 | Sughrue Mion, PLLC | 代理人 | Sughrue Mion, PLLC |
| 主权项 | 1. A gradual disintegration-type and matrix-type pharmaceutical solid preparation comprising: (a) tolvaptan; (b) calcium polycarbophil; and (c) a sugar and/or sugar alcohol, the (c) sugar and/or sugar alcohol being at least one member selected from the group consisting of trehalose, lactitol, maltose, maltitol, sucrose, sorbitol, xylitol, erythritol, mannitol, lactose, and isomaltooligosaccharide. | ||
| 地址 | Tokyo JP | ||