发明名称 Fused aminodihydrothiazine derivatives
摘要 The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine; R is monofluoromethyl or difluoromethyl; and pharmaceutically acceptable salts thereof; which compound has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.;
申请公布号 US9175013(B2) 申请公布日期 2015.11.03
申请号 US201213979961 申请日期 2012.01.19
申请人 Eisai R&D Management Co., Ltd. 发明人 Takaishi Mamoru;Ishida Tasuku
分类号 C07D513/04;A61K31/542;A61K45/06 主分类号 C07D513/04
代理机构 Fish & Richardson P.C. 代理人 Fish & Richardson P.C.
主权项 1. A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein X is hydrogen or fluorine;R is monofluoromethyl or difluoromethyl.
地址 Tokyo JP