| 发明名称 |
inibidores de mmp-12 e mmp-13 com base em ácido hidroxâmico seletivo |
| 摘要 |
The present invention provides a compound of formula (I) said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I). |
| 申请公布号 |
BRPI0915762(A2) |
申请公布日期 |
2015.11.03 |
| 申请号 |
BR2009PI15762 |
申请日期 |
2009.07.13 |
| 申请人 |
NOVARTIS AG |
发明人 |
LESLIE WIGHTON MCQUIRE;MICHAEL SHULTZ;OLIVIER ROGEL;RIBEN ALBERTO TOMMASI;SVEN WEILER |
| 分类号 |
A61K31/18;A61K31/445;A61P29/00;A61P35/00;C07C311/19;C07C311/29;C07C311/44;C07D207/48;C07D211/96;C07D213/53;C07D215/36;C07D223/06;C07D277/06;C07D277/80;C07D309/06 |
主分类号 |
A61K31/18 |
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