发明名称 RAMUCIRUMAB ET SES DÉRIVÉS PHARMACEUTIQUEMENT ACCEPTABLES (CYRAMZA)
摘要 <p>The application provides antibodies that bind to KDR with an affinity comparable to or higher than human VEGF, and that neutralize activation of KDR. Antibodies include whole immunoglobulins, monovalent Fabs and single chain antibodies, multivalent single chain antibodies, diabodies, triabodies, and single domain antibodies. The application further provides nucleic acids and host cells that encode and express these antibodies.</p>
申请公布号 LU92710(I2) 申请公布日期 2015.11.02
申请号 LU20150092710C 申请日期 2015.05.06
申请人 IMCLONE LLC 发明人
分类号 C12N15/09;A61K39/395;A61K45/00;A61P35/00;A61P43/00;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10 主分类号 C12N15/09
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