发明名称 COMBINATORIAL THERAPY INVOLVING ALPHA5BETA1 ANTAGONISTS
摘要 <p>The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.</p>
申请公布号 SI1989231(T1) 申请公布日期 2015.10.30
申请号 SI20070031683T 申请日期 2007.03.21
申请人 GENENTECH, INC., 发明人 CHUNTHARAPAI ANAN;PLOWMAN GREG;TESSIER-LAVIGNE MARC;WU YAN;YE WEILAN
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