发明名称 |
FC-RECEPTOR BASED AFFINITY CHROMATOGRAPHY FC- |
摘要 |
Herein is reported the use of an immobilized non-covalent complex of a neonatal Fc receptor (FcRn) and beta-2-microglobulin (b2m) as affinity chromatography ligand in general and, for example, for the determination of the in vivo half-live of an antibody by determining the ratio of the retention times of the antibody and a reference antibody. |
申请公布号 |
HK1203435(A1) |
申请公布日期 |
2015.10.30 |
申请号 |
HK20150104045 |
申请日期 |
2015.04.27 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
FALKENSTEIN, ROBERTO;HERTENBERGER, HUBERT;RUEGER, PETRA;SCHLOTHAUER, TILMAN |
分类号 |
B01D;C07K |
主分类号 |
B01D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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