发明名称 |
POLYMORPHOUS FORMS OF RIFAXIMIN, PROCESSES FOR THEIR PRODUCTION AND USE THEREOF IN MEDICINAL PREPARATIONS |
摘要 |
<p>Crystalline polymorphic forms of rifaximin (INN), referred to as rifaximinαand rifaximinβ, and a poorly crystalline form referred to as rifaximinγ, useful in the production of medicaments containing rifaximin for the oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.</p> |
申请公布号 |
RS20150292(A1) |
申请公布日期 |
2015.10.30 |
申请号 |
RS2015P000292 |
申请日期 |
2004.11.04 |
申请人 |
ALFA WASSERMANN S.P.A. |
发明人 |
VISCOMI, GIUSEPPE C.;CAMPANA, MANUELA;BRAGA, DARIO;CONFORTINI, DONATELLA;CANNATA, VINCENZO;RIGHI, PAOLO;ROSINI, GOFFREDO |
分类号 |
A61K31/44;C07D498/22;A61K31/395;A61K31/4188;A61K31/4353;A61K31/437;A61P31/00;A61P31/04 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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