发明名称 |
C-19 MODIFIED TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY. |
摘要 |
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-19 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas (I) and (II), wherein R1 is as defined herein and does not represent either an isopropyl or isopropenyl group: (Formula (I)) and (Formula (II)). These compounds are useful for the treatment of HIV and AIDS. |
申请公布号 |
MX2015010003(A) |
申请公布日期 |
2015.10.30 |
申请号 |
MX20150010003 |
申请日期 |
2014.02.04 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
NICHOLAS A. MEANWELL;ZHENG LIU;ALICIA REGUEIRO-REN;JACOB SWIDORSKI;NY SIN;BRIAN LEE VENABLES |
分类号 |
C07J63/00;A61K31/18;A61K31/56 |
主分类号 |
C07J63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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