发明名称 IMPROVED STABLE AQUEOUS FORMULATION OF (E)-4-CARBOXYSTYRYL-4-CHLOROBENZYL SULFONE
摘要 <p>An aqueous pharmaceutical solution composition comprising between about 20 mg/ml to about 100 mg/ml of a radioprotectiveα,β-unsaturated aryl sulfone, a cosolvent comprising polyethylene glycol (PEG), polypropylene glycol, polyglycerol, DMA, propylene glycol, glycerol, ethanol, sorbitol, isopropyl alcohol, or a combination thereof in an amount between about 25% and about 90% w/v, and a water soluble Vitamin E derivative, wherein the composition has a pH within the range of about 7.0 to about 9.5.</p>
申请公布号 SI2552199(T1) 申请公布日期 2015.10.30
申请号 SI20110030564T 申请日期 2011.03.24
申请人 ONCONOVA THERAPEUTICS, INC. 发明人 MANIAR MANOJ
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