发明名称 |
Highly active nucleoside derivative for the treatment of HCV |
摘要 |
A deuterated nucleoside analog of the formula and the pharmaceutically acceptable salts thereof are provided by this disclosure. The disclosure also includes pharmaceutical compositions comprising a compound or salt of the formula and a carrier. Compounds and salts of this formula are useful for treating viral infections, including HCV infections. A method for treating a host afflicted with hepatitis C or other disorders is also presented that includes administering an effective treatment amount of a nucleoside or nucleotide that has deuterium with at least 50% enrichment at the 5'-position of the nucleoside or nucleotide. |
申请公布号 |
AU2014250762(A1) |
申请公布日期 |
2015.10.29 |
申请号 |
AU20140250762 |
申请日期 |
2014.04.14 |
申请人 |
ACHILLION PHARMACEUTICALS, INC. |
发明人 |
DESHPANDE, MILIND;WILES, JASON ALLAN;HASHIMOTO, AKIHIRO;PHADKE, AVINASH |
分类号 |
C07H19/067;A61K31/7072;A61P31/14;C07B59/00 |
主分类号 |
C07H19/067 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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