发明名称 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
摘要 The present invention discloses compounds according to Formula I: Wherein R1a, R1b, R2, R4, R5, R6a, R6b, R7, R8, W, X, Cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (NPP2 or ENPP2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, neurodegenerative diseases, dermatological disorders, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.
申请公布号 SG11201507224R(A) 申请公布日期 2015.10.29
申请号 SG11201507224R 申请日期 2014.03.07
申请人 GALAPAGOS NV 发明人 DESROY, NICOLAS;HECKMANN, BERTRAND;BRYS, REGINALD CHRISTOPHE XAVIER;JONCOUR, AGNÈS;PEIXOTO, CHRISTOPHE;BOCK, XAVIER
分类号 C07D471/04;A61K31/437;A61P9/00;A61P11/00;A61P25/28;A61P29/00;A61P35/00;A61P37/00 主分类号 C07D471/04
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