| 主权项 |
1. A method of assessing the severity of acute kidney injury (AKI) injury in a subject following cardiac surgery, comprising:
measuring one or more markers from Table 1 and/or Table 2 in a biological sample obtained from the subject within 24 hours following cardiac surgery; generating a risk score based on the measured level of one or more of the biomarkers from Table 1, wherein if the risk score exceeds a predefined cutoff, the subject is determined to be at risk of developing RIFLE I/F; and optionally, if the subject is not determined to be at risk of developing RIFLE I/F, further generating a risk score based on the measured level of one or more of the biomarkers selected from Table 2, wherein if the risk score exceeds a predefined cutoff, the subject is determined to be at risk of developing RIFLE R or if the risk score is below the predefined cutoff the subject is determined not to be at risk of developing AKI. |
