发明名称 |
COMBINATIONS OF A PI3K/AKT INHIBITOR COMPOUND WITH AN HER3/EGFR INHIBITOR COMPOUND AND USE THEREOF IN THE TREATMENT OF A HYPERPROLIFERATIVE DISORDER |
摘要 |
The invention provides combinations comprising GDC-0068 or GDC-0941, or a pharmaceutically acceptable salt thereof and ME-HD7945A. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer (e.g., triple negative breast cancer). |
申请公布号 |
US2015306216(A1) |
申请公布日期 |
2015.10.29 |
申请号 |
US201314649889 |
申请日期 |
2013.12.09 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
BASELGA Jose;SCALTRITI Maurizio |
分类号 |
A61K39/395;A61J1/00;G01N33/574;A61K31/517;A61K31/5377 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
1. A combination of GDC-0068 or GDC-0941, or a pharmaceutically acceptable salt thereof, and MEHD7945A, for the therapeutic treatment of a hyperproliferative disorder. |
地址 |
Boston MA US |