发明名称 COMBINATIONS OF A PI3K/AKT INHIBITOR COMPOUND WITH AN HER3/EGFR INHIBITOR COMPOUND AND USE THEREOF IN THE TREATMENT OF A HYPERPROLIFERATIVE DISORDER
摘要 The invention provides combinations comprising GDC-0068 or GDC-0941, or a pharmaceutically acceptable salt thereof and ME-HD7945A. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer (e.g., triple negative breast cancer).
申请公布号 US2015306216(A1) 申请公布日期 2015.10.29
申请号 US201314649889 申请日期 2013.12.09
申请人 THE GENERAL HOSPITAL CORPORATION 发明人 BASELGA Jose;SCALTRITI Maurizio
分类号 A61K39/395;A61J1/00;G01N33/574;A61K31/517;A61K31/5377 主分类号 A61K39/395
代理机构 代理人
主权项 1. A combination of GDC-0068 or GDC-0941, or a pharmaceutically acceptable salt thereof, and MEHD7945A, for the therapeutic treatment of a hyperproliferative disorder.
地址 Boston MA US