发明名称 HYDRAZALINE HYDORCHLORIDE PELLETS AND METHOD OF PREPARATION
摘要 Embodiments of a hydrazaline hydrochloride composition for treatment of hypoertension in humans each provide sustained release of hydralazine hydrochloride administered in the form of pellets, granules and tablets. Methods of preparation are disclosed.
申请公布号 US2015306097(A1) 申请公布日期 2015.10.29
申请号 US201514620405 申请日期 2015.02.12
申请人 Gorrepati Navaneeta K. 发明人 Gorrepati Navaneeta K.
分类号 A61K31/502;A61K9/50;A61K47/10;A61K47/36;A61K47/12;A61K47/38;A61K47/32;A61K47/26;A61K9/00;A61K47/02 主分类号 A61K31/502
代理机构 代理人
主权项 1. A sustained release pharmaceutical composition of hydralazine hydrochloride comprising: 20-40% by weight of active drug content of hydralazine hydrochloride; 40-70% by weight of core content; 10-30% by weight of diluent; 1.5-3.2% by weight of binding agent; 4.2-6.8% by weight of control polymer; 0.22-0.53% by weight of film forming agent; 3.2-5.6% by weight of glidant; and a solvent.
地址 DeSoto TX US